There's alot of questions about what caliber is best for hunting? And how much 'gun' is enough? Just based on my experience, where you hunt and the size of the game are the determining factors. I've hunted a lot in very heavy brush, deer and pigs, nothing over 300 lbs. I've killed most of what I shot with the .45 Colt in handgun and carbine. I haven't shot anything over 50 yards in very many years. I do have a .38-55 if I get invited to sit in a blind (hasn't happened in awhile!). If I were to go to Africa I'd need way more in power. If I were to go hunting out on the rolling plains I'd need something real flat shooting. For now, the .45 Colt works just fine.