The Ruger P345 is an attempt by Ruger to improve their line to compete with other guns for being attractive, somewhat compact, and offer desireable features. I handled one and was not impressed.
HOWEVER - It was solely based on my opinions and taste. The Rugers are decent guns. If it suits you, it's a fine choice and an excellent price.
Based on that price, I would also continue to consider a Makarov, Bersa Thunder 380, Firestorm/Llama 1911 clone, Arcus Hi-Power based 9mm, and possibly others. But it's your call and the P345 isn't a bad choice at all.