When I was younger my father owned a meat processing plant. On Tuesdays and Thursdays we would slaughter. There were a few times that I remember where some Rancher would wrangle a steer or two that broke away from the herd and became wild. We had one break out of the stock pens and go on a rampage through town and by the time they caught up to him he was headed towards an Elementary school with children at play. He was put down and brought back by a Front loader. Another time there was a steer that got loose inside the plant and wreaked havoc on the kill floor injuring a few of the employees. He broke through the bollards bending the galvanized steel posts to get out of the Kill stall. After that larger ones were installed and filled with concrete.
When I hunted this Bull it was on foot but we were able to drive a truck within about 50yds of him where he fell. If I had my side by side there it would have been an easy drive right up to him and work on him. We cut him up and would carry out the quarters. The rear quarters were the challenge and took us both to lift them to where you could shoulder him, breaking your back in the process
I used the 375 Ruger because I wanted something that generated some serious energy in the 5,000ftlb range and would stop him quickly. The friend I was with used a 45-70 to kill his a year prior. He said he had to take multiple shots to drop it and it kept moving further and further away from where they could get a vehicle to. He told me if I had something big to bring it so it wouldn't be a repeat of his pack out.
I'm not saying that the 45-70 isn't capable if killing a Bull or large animal so don't anyone think that's the case.