It might match up with the guide rails, but the Glock22 is a .40SW and the 17 is a 9mm. I think the question is, "Will the barrel match up with the slide." I don't know the answer to that. Is the hole cut in the slide for a 9mm glock the same as one cut for a .40SW glock? How does the outter circumference of a Glock 9mm barrel match up in relation to a Glock .40SW barrel? I don't know off hand, but will look into. I've never heard of the 24C model, but will look into it.